Enrofloxacin ndi mankhwala ophera mabakiteriya ambiri omwe amapha ziweto zomwe zili mgulu la flurofenolone. Escherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Actinobacillus pleuropneumoniae, Erysipelas, Proteus, Serratia marcescens, Corynebacterium pyogenes, Portella septicarum Ili ndi zotsatira zabwino pa mabakiteriya, Staphylococcus aureus, mycoplasma, chlamydia, ndi zina zotero, koma ili ndi zotsatira zochepa pa Pseudomonas aeruginosa ndi Streptococcus komanso zotsatira zochepa pa mabakiteriya omwe alibe mabakiteriya. Ili ndi zotsatira zodziwika bwino za antibacterial pa mabakiteriya omwe ali ndi vuto la mabakiteriya.

Mankhwalawa amalowa mwachangu komanso kwathunthu kudzera mu jakisoni wa mu mnofu. Kupezeka kwa mankhwalawa ndi 91.9% mwa nkhumba ndi 82% mwa ng'ombe zamkaka. Amafalikira kwambiri mu nyama ndipo amatha kulowa mosavuta mu minofu ndi madzi amthupi. Kupatula madzi am'mitsempha, kuchuluka kwa mankhwalawa m'thupi pafupifupi kumakhala kwakukulu kuposa komwe kumakhala m'magazi. Kagayidwe ka chiwindi kameneka kamakhala kokulirapo kuposa komwe kali m'magazi. Kagayidwe ka chiwindi kameneka kamakhala ndi gawo lofunika kwambiri pakuchotsa gulu la ethyl la mphete ya 7-crosin kuti apange ciprofloxacin, kutsatiridwa ndi okosijeni ndi glucuronic acid conjugation, makamaka yotulutsidwa kudzera mu impso (ndi kutulutsa kwa tubular ya impso ndi kusefa kwa glomerular), 15% mpaka 50% Yotulutsidwa mosasinthika mu mkodzo. Chotsani theka la moyo wa munthu. Moyo wa munthu umasiyana kwambiri m'mitundu yosiyanasiyana ya nyama ndi njira zosiyanasiyana zoperekera. Kuchotsa theka la moyo wa munthu pambuyo pobayidwa mu mnofu.

Kuyanjana kwa mankhwala: (1) Mankhwalawa amakhala ndi mphamvu yogwirizana akaphatikizidwa ndi shuga wa amino kapena penicillin wochuluka. (2) Ma ayoni achitsulo cholemera monga Ca2+, Mg2+, Fe; ndi Al Children amatha kuyanjana ndi mankhwalawa ndikukhudza kuyamwa. (3) Akagwiritsidwa ntchito limodzi ndi theophylline ndi caffeine, kuchuluka kwa mapuloteni a plasma kumatha kuchepetsedwa, kuchuluka kwa theophylline ndi caffeine m'magazi kumawonjezeka modabwitsa, ndipo ngakhale zizindikiro za poizoni wa theophylline zimatha kuchitika. (4) Mankhwalawa ali ndi mphamvu yoletsa ma enzymes a chiwindi ndipo amatha kuchepetsa kuchuluka kwa mankhwala omwe amasinthidwa kwambiri m'chiwindi.

Ntchito ndi kagwiritsidwe ntchito: Mankhwala opha tizilombo a Flufenolone. Amagwiritsidwa ntchito pa matenda a bakiteriya ndi matenda a mycoplasma m'ziweto ndi nkhuku.