Albendazole Bolus 2500mg
Albendazole ndi mankhwala opangira anthelmintic omwe ali m'gulu la benzimidazole-derivatives omwe amagwira ntchito motsutsana ndi nyongolotsi zambiri komanso pamlingo wapamwamba kwambiri komanso motsutsana ndi akulu akulu a chimfine.
Pharmacological Action
Albendazole pamodzi ndi eelworms microtubule mapuloteni ndi ntchito.Pambuyo pa albenzene kuphatikizidwa ndi β-tubulin, imatha kuletsa dimerization pakati pa albenzene ndi α tubulin kusonkhana mu ma microtubules.Ma microtubules ndiye maziko a ma cell ambiri.Kugwirizana kwa Albendazole ndi nematodes tubulin ndikwapamwamba kwambiri kuposa kugwirizana kwa mammalian tubulin, kotero kuti kawopsedwe kwa mammalian ndi ochepa.
Zizindikiro
Prophylaxis ndi chithandizo cha nyongolotsi mu ng'ombe ndi ng'ombe monga:
Matenda a m'mimba:Bunostomum, Cooperia, Chabertia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides ndi Trichostrongylus spp.
Lung worms:Dictyocaulus viviparus ndi D. filaria.
Tapeworms:Moniza spp.
Chiwindi-fluke:wamkulu Fasciola hepatica.
Albendazole alinso ndi ovicidal zotsatira.
Zotsutsana
Administration m`masiku 45 oyembekezera.
Zotsatira zake
Hypersensitivity zimachitikira.
Mlingo
Kuwongolera pakamwa.
Kwa roundworms, tapeworms:
Ng'ombe / njati / kavalo / nkhosa / mbuzi: 5mg/kg kulemera kwa thupi
Galu / mphaka: 10 mpaka 25mg / kg kulemera kwa thupi
Za flukes:
Ng'ombe / njati: 10mg / kg thupi
Nkhosa/mbuzi: 7.5mg/kg kulemera kwa thupi
Ng'ombe ndi ng'ombe: 1 bolus pa 300 kg.kulemera kwa thupi.
Kwa chiwindi-fluke:
1 bolus pa 250 kg.kulemera kwa thupi.
Chenjezo
Khalani kutali ndi ana.
Nthawi Yotsimikizira
3 zaka.
Nthawi Zochotsa
- Za nyama:12 masiku.
- Za mkaka:4 masiku.
Kusungirako
Sungani pamalo ozizira kwambiri, ouma otetezedwa ku kuwala.
Zogwiritsa Ntchito Zowona Zanyama Pokha, Khalani kutali ndi ana
